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A light-triggered protein secretion system
Sister kinetochores (green dots) at the edge of a PtK1 cell (left) move little, whereas kinetochores near the middle of the cell (right) oscillate.

Civelekoglu-Scholey et al. explain why some metaphase chromosomes...' );return false" > Why metaphase chromosomes wander
The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A
Bil1 (green) and Bud6 (red) colocalize at the bud necks (arrowheads) of yeast cells.

Graziano et al. reveal a new mechanism for controlling actin nucleation.

Proteins that spur actin assembly often work...' );return false" > Three's not a crowd for actin nucleators
Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance
1).

FOCAL POINT (Left to right) Libor Macurek, Zdenek Kleibl, Petra Kleiblova, and colleagues (not...' );return false" > Making short work of p53
Ligand-induced activation of a formin-NPF pair leads to collaborative actin nucleation
Victor Ambros: The broad scope of microRNAs
307–322.

The DMSO Fn and Act panels for Icap-1^+/+ and Icap-1^–/– in the original version of Fig. 1 D were duplicates of the Fn and Act...' );return false" > Osteoblast mineralization requires {beta}1 integrin/ICAP-1-dependent fibronectin deposition
http://dx.doi.org/10.1083/jcb.201211160), have taken different routes to discover a role for Syntaxin 17 in the maturation of autophagosomes.
' );return false" > Route to destruction: Autophagosomes SNARE lysosomes
Tpr (red) accumulates in the nuclei of cells from a healthy person (left), but it remains in the cytoplasm of cells from an HGPS patient (right).

A mutant protein responsible for Hutchinson-Gilford...' );return false" > Progerin guilty of size discrimination
The cell biology of disease: Cellular and molecular mechanisms underlying muscular dystrophy
Dynamic bonds and polar ejection force distribution explain kinetochore oscillations in PtK1 cells
Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint
p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
The asymmetric segregation of damaged proteins is stem cell-type dependent
97–109.

The Control anti-αvβ3 micrograph in the original version of Fig. 5 A was a duplicate of the Control micrograph in Fig. 6 A. The authors...' );return false" > Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through {alpha}2{beta}1 integrin
Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila
p53 integrates host defense and cell fate during bacterial pneumonia
Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport
Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins

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